MedPage Today March 13, 2025
Kelly Dunn, PhD, MBA

— Progress in managing depression has far outpaced management of opioid use disorder

Six decades ago, researchers identified two transformative medical strategies that provided immense hope for managing two major public health problems. One was introducing the concept that depression originated from altered levels of brain chemicalsopens in a new tab or window; the other was determining that addiction to opioid drugs like heroin could be managed or even curedopens in a new tab or window through treatments that targeted opioid physical dependence.

Since then, we’ve seen major success with the management of clinical depression with seven different classes of medicationsopens in a new tab or window, 30 formally approved compoundsopens in a new tab or window, and several more...

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