Andreessen Horowitz February 11, 2021
The second coming of RNA medicines
The Moderna and Pfizer/BioNTech COVID vaccines mark a major milestone – not just for this pandemic, but for their entire therapeutic class: RNA-based drugs. While companies like Alnylam, Sarepta, and IONIS have received FDA approval for a handful of RNA therapeutics, the design of new RNA drugs has been slower than promised due to some technical and practical challenges, so the excitement for this class has waned over the last two decades. The COVID mRNA vaccines have now re-ignited interest in a huge way – and perhaps most importantly – demonstrated that many of the challenges that plagued these early companies can be resolved. In this blog post, bio deal team partner Judy Savitskaya...
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