BioPharma Dive September 4, 2024
Jonathan Gardner

Medicines that can rev up the immune system against tumors have reshaped expectations of what cancer treatment can accomplish. Their success has hit limits, however.

Nine years ago, Lisa Haines got news no one wants to hear. Her doctors said her lung cancer, which chemotherapy had earlier arrested, was growing again.

The Massachusetts resident began planning for family events she thought would be her last, like her son’s wedding and a Thanksgiving trip. Her doctor didn’t give up, however. She recommended Haines try an immunotherapy called Opdivo, one of what was then a new class of drugs that works by enlisting the body’s immune system to fight cancer.

In December 2015, Haines became the first patient at Addison Gilbert Hospital...

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