Eric Topol February 14, 2025
Now 6 Ongoing Clinical Trials in the United States
It’s a huge unmet need to prevent Covid infections and block transmission. A nasal spray vaccine has the best shot of achieving this goal, as we’ve seen in many experimental models of candidate vaccines. I’ve reviewed the topic, rationale, and progress previously at Ground Truths, but it has been awhile and there are some interesting new developments, along with concerns about the jeopardy of these program with the new US administration. While SARS-CoV-2 circulating levels are relatively low at the moment, that is not likely to last as the virus’s evolution marches on.
This week the Ocugen Phase 1 trial of an adenovirus-vector spike protein nasal vaccine was given the go...