Pharmacy Times September 11, 2024
Robert Danby, DPhil, MBChB (Hons), MRCP, FRCPath

This year the world’s first stem cell register celebrates its 50th anniversary.

When Anthony Nolan was born in 1971 with Wiskott-Aldrich syndrome, a rare inherited immunodeficiency disorder, his mother Shirley was told a bone marrow transplant was his only chance of survival. Known today as a haematopoietic cell transplant (HCT), the procedure would involve replacing his affected bone marrow with that of a healthy human leukocyte antigen (HLA)–matched donor. But with no siblings, he would need an unrelated donor.

At the time, there was no system for finding potential donors for people like Anthony. Desperate for a match for her son, Shirley set up the world’s first register of people willing to donate their bone marrow to those with blood...

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