Eric Topol July 21, 2024

How can we know the primacy of our immune response for health yet be unable to measure it?

It is startling that here we are in 2024, recognizing how critical our immune system is for protecting us against infections and major diseases, such as cancer, and how it tells us about our aging process (immunosenescence), yet we have no informative clinical test to get at it.

The crude way we can assess our immune system is from a complete blood count (CBC) looking at the white blood cell (neutrophil) to lymphocyte ratio (NLR). It is a very rough assessment of the balance between inflammation (neutrophil count) vs immune system (lymphocyte count) and is associated with a poor prognosis for cancer,...

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