JAMA Network July 5, 2023
There’s no question that the next version of the COVID-19 vaccine in the US will contain components of Omicron subvariant XBB.1.5.
What’s still up in the air, though, is who should get the shot when it debuts this fall.
On June 15, members of the US Food and Drug Administration’s (FDA) Vaccine and Related Biological Products Advisory Committee (VRBPAC) voted unanimously to recommend updating the COVID-19 vaccine composition to a monovalent XBB lineage.
On June 16, the FDA announced that it had advised manufacturers planning to update their COVID-19 vaccines that they should specifically target XBB.1.5. Scientists from Moderna, Novavax, and Pfizer had told the FDA and its advisory committee that their XBB.1.5 monovalent vaccines could be ready...
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