Eric Topol July 13, 2024
Predicting and Tracking Organ-Specific Aging, Health and Disease
Late last year, I interviewed Tony Wyss-Coray of Stanford University, who is doing pioneering work with an international team on proteomic organ clocks. His seminal paper, which prompted our conversation, was on the cover (below) at Nature. Since that publication there have been 2 new organ clock preprints based on the UK Biobank resource, the most recent one by Tony and his collaborators. In this edition of Ground Truths, I’m going to briefly review all 3 reports and explain why I think this will be one of the most important advances for tracking health and disease for the future.
The First Study
From 5 cohorts (3 healthy, 2 with Alzheimer’s disease) involving...
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