Study: COVID-19 mRNA booster vaccinations increased and sustained antibody responses

Medical Xpress March 23, 2023
By Tokyo Metropolitan Institute of Medical Science

Booster vaccinations against SARS-CoV-2 are being promoted worldwide to counter the coronavirus disease 2019 (COVID-19) pandemic. Recent studies on the effectiveness of the third dose of the vaccine found improved efficacy against SARS-CoV-2 infection and a reduction in hospitalization. However, most studies on the effect of the third vaccination have been limited to a relatively short period of time after the third dose, and few longitudinal analyses of the effects of the third vaccination with an anti−SARS-CoV-2 vaccine have been reported.

Researchers from Tokyo Metropolitan Institute of Medical Science analyzed the longitudinal effect of the third SARS-CoV-2 mRNA vaccination on antibody responses in healthcare workers in Tokyo, Japan. Additionally, antibody responses induced by the fourth vaccination were analyzed.

The levels...

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