STAT June 23, 2021
The unprecedented rapid development and distribution of Covid-19 vaccines worldwide has brought new visibility to how vaccines are produced, packaged, and distributed. The world learned about the vaccine cold chain, for example, as people monitored rollout plans for Covid-19 vaccines and the added logistics that came with keeping them cold.
Since then, many people have asked this question: Why don’t we have more thermostable, easy-to-administer vaccines?
Though a number of pharmaceutical companies are working on advancing these kinds of products, the science is complex and decisions often involve evaluating cascading tradeoffs.
A balancing act between stability and simplicity
Vaccines that don’t need to be kept frozen or refrigerated would be ideal. But because they are biological products, there are no...