STAT July 26, 2022
Expanding new medical treatments requires pushing — and sometimes breaking — the boundaries of what currently defines therapeutics. One of those boundaries is the very definition of a cell.
Until recently, cells were all-natural beings, living cell begetting living cell. That’s changing as synthetic biologists and engineers are learning to create synthetic cells that may someday change how a range of diseases are treated.
Synthetic cells are membrane-enclosed systems constructed from nonliving parts. They can contain engineered genomes, artificial organelles, and complex enzyme pathways. Acting as microscopic bioreactors, they present opportunities to design and deliver medicines that uniquely match an individual’s DNA and disease profile.
Researchers across the U.S. and around the globe are advancing the understanding, development, and use...
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