Health IT Analytics December 16, 2020
A new RNA drug discovery tool could help researchers develop precision medicine treatments for incurable diseases.
A new tool that focuses on RNA could accelerate the development of precision medicine treatments for incurable diseases, including a type of metastatic breast cancer, according to a study published in Proceedings of the National Academy of Sciences (PNAS).
Incurable diseases – also referred to as undruggable diseases – typically have targets that lie on a protein molecule that folds inward, or in a way that protects the active site from potential treatments.
To address this issue, a team from Scripps Research developed a tool that avoids these proteins completely, and modifies elements involved in their construction and regulation instead. The tool, called Chem-CLIP-Fragment...
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