Medical Xpress June 29, 2022
Penn State College of Medicine

A new machine learning method to model gene expression levels might improve the identification of genes that cause human diseases, according to a new study by Penn State College of Medicine researchers. Through information from the three-dimensional (3D) structure of genomes and epigenetics—how genes and environment jointly influence diseases—the investigators were able to identify genes associated with complex traits and diseases. These identified disease genes also help to nominate drugs that may be repurposed to treat new disorders.

Developing and approving new prescription medications can be a costly and time-consuming process. However, findings from this study could partially change that moving forward. According to investigators, instead of developing new medicines, could save time and money by repurposing drugs...

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