BioPharma Dive November 9, 2021
Encouraged by Moderna’s success, Flagship Pioneering has been busy creating startups like Alltrna, which is researching how to make medicines from transfer RNA.
Long before we knew how they did it, human cells had refined the process for making proteins, the microscopic workers needed for pretty much everything our bodies do.
First, a special enzyme finds the instructions for a protein in our DNA. It then produces a piece of genetic information called messenger RNA, or mRNA, that acts as a template for another part of the cell, the ribosome, telling it what building blocks are required for the protein and what order they go in.
At the tail end of this operation are transfer RNAs, which, as the name...
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