Medical Xpress July 29, 2021
The Biomedical Genomics laboratory at IRB Barcelona has developed a computational tool that identifies cancer driver mutations for each tumor type.
This and other developments produced by the same lab seek to accelerate cancer research and provide tools to help oncologists choose the best treatment for each patient.
The study has been published in the journal Nature.
Each tumor—each patient—accumulates many mutations, but not all of them are relevant for the development of cancer. Researchers led by ICREA researcher Dr. Núria López-Bigas at IRB Barcelona have developed a tool, based on machine-learning methods, that evaluates the potential contribution of all possible mutations in a gene in a given type of tumor to the development and progression of cancer.