KevinMD July 4, 2023
Between 2013 and 2016, 49.1 percent of U.S. adults surveyed had attempted to lose weight within the last 12 months. Weight loss medications have reached the public eye in popular culture and practice. To be considered effective in a clinical trial by the FDA, the drug candidate must demonstrate a statistically significant difference in mean weight loss between the active product and placebo-treated group of at least five percentage points. Additionally, the proportion of subjects who lose 5 percent or more of their baseline body weight must be at least 35 percent of the overall group, approximately twice the proportion of the placebo-treated group, with a statistically significant difference. The FDA states that the source of this weight loss should...
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