Health IT Analytics August 27, 2020
The findings could help explain why some individuals with high genetic disease risk don’t go on to develop genetic conditions.
In people with a single-gene variant that contributes to high genetic disease risk – specifically for heart disease, breast cancer, or colorectal cancer – the rest of the genome can alter that risk, according to a study published in Nature Communications.
Some individuals are genetically predisposed to disease, but these disease predictions aren’t always accurate as not everyone carrying these high-risk single-gene variants develops the disease.
A team from the Broad Institute of MIT and Harvard, Massachusetts General Hospital (MGH), Harvard Medical School collaborated with IBM Research and Color to determine why this occurs. The group focused on three...
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