Big data and health

The digital health revolution is here. Innovations include not only the collection and analysis of electronic health records and personal genomes, but also diverse physiological and molecular measurements in individuals at a level that has not previously been possible. Our recent studies, in which we deep-profiled 109 people for a median of nearly 3 years and made 49 major health discoveries (67 if hypertension is included) affecting 53 people, shows the value of big data and active monitoring. Many health discoveries involved disease risk prediction from genome sequencing, but most involved early detection of disease before symptom onset. Many of these findings were highly impactful, such as early detection of cardiomyopathy, lymphoma, and two precancerous conditions (monoclonal gammopathy of undetermined...