AI accelerates discovery of neurodevelopmental disorder-associated genes

Medical Xpress February 26, 2025
Baylor College of Medicine

Researchers have developed an artificial intelligence (AI) approach that accelerates the identification of genes that contribute to neurodevelopmental conditions such as autism spectrum disorder, epilepsy and developmental delay.

This new powerful computational tool can help fully characterize the genetic landscape of neurodevelopmental disorders, which is key to making accurate molecular diagnosis, elucidating disease mechanisms and developing targeted therapies.

The study appears in The American Journal of Human Genetics.

“Although researchers have made major strides in identifying different genes associated with neurodevelopmental disorders, many patients with these conditions still do not receive a genetic diagnosis, indicating that there are many more genes waiting to be discovered,” said first and co-corresponding author Dr. Ryan S. Dhindsa, assistant professor of pathology and immunology...